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Northeast Structural Genomics Consortium

Acronym or abbreviated name:
U.S. mailing address:
CABM Structural Bioinformatics Laboratory, Gaetano T. Montelione, 679 Hoes Lane, Piscataway, NJ 08854
Telephone number:
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Web site address:
Gaetano Montelione
Contact email address:
Purpose of center:
During the pilot phase, this academic consortium determined more than 200 structures of both prokaryotic and eukaryotic proteins, including human proteins, using X-ray crystallography and solution-state NMR spectroscopy. It also developed several new technologies for eukaryotic protein production and protein structure analysis. In PSI-2, the consortium plans to solve both prokaryotic and eukaryotic structural representatives from the major domain families constituting the eukaryotic proteome. Its biological-focus project targets networks of co-functioning proteins (BioNets) involved in developmental biology and cancer.
Columbia University, Hauptman Woodward Medical Research Institute, Ontario Cancer Institute at the University of Toronto, Pacific Northwest National Laboratories, Rutgers University, Robert Wood Johnson Medical School at the UMDNJ, Weill Medical School at Cornell University, and Yale University

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